Total Access Admin can monitor multiple databases (with the same security settings) simultaneously in one screen. Up to 100 databases can be monitored at one time.
In the Access 2007 version and earlier, each database needed to be opened in a separate instance of Total Access Admin. That is still necessary if your databases use different workgroup settings, or you want to perform different actions on each database.
You can have an unlimited number of instances of Total Access Admin open on the same machine to monitor all your databases. They can all log the user activity into the same database.